The United States has launched a far-reaching federal initiative that aims to redefine the nation’s scientific and technological future.
The new directive, known as the Genesis Mission, is being framed as one of the most ambitious US research efforts in decades – anchored in the accelerating power of AI computing.
Announced in a White House Executive Order, the mission will be spearheaded by the Department of Energy and is designed to radically expand America’s scientific capabilities, sharpen global competitiveness, and secure long-term technological dominance.
The administration says the initiative will effectively “double the productivity” of US science and engineering over the next ten years.
Commenting on the initiative, Secretary of Energy Chris Wright said: “Throughout history, from the Manhattan Project to the Apollo mission, our nation’s brightest minds and industries have answered the call when their nation needed them.
“Now, the United States is calling on them once again. The Genesis Mission will unleash the full power of our National Laboratories, supercomputers, and data resources to ensure that America is the global leader in artificial intelligence and to usher in a new golden era of American discovery.”
An AI computing ecosystem built for breakthroughs
The Genesis Mission builds on President Trump’s earlier Executive Order aimed at removing regulatory obstacles to American AI development, as well as America’s AI Action Plan released earlier this year.
Together, these directives form a sweeping national blueprint to reduce dependence on foreign technology, unlock advanced research, and accelerate scientific progress.
Secretary of Energy Wright has appointed Under Secretary for Science Darío Gil to lead the mission.
Under his direction, the Department of Energy’s 17 National Laboratories will join forces with private-sector technology leaders and major academic institutions to construct an unprecedented integrated discovery platform.
The system – described by officials as the most intricate scientific instrument ever attempted – will fuse the nation’s top supercomputers with advanced AI computing frameworks, next-generation quantum technologies, and cutting-edge research facilities.
In total, more than 40,000 federal scientists, engineers, and technical specialists are expected to contribute, alongside US industry partners developing the technologies that will shape global innovation for decades.
Targeting energy, science, and security
The administration has identified three primary national priorities for the Genesis Mission.
First, the initiative aims to secure US energy leadership by deploying AI tools to accelerate progress in fusion, next-generation nuclear systems, and modernised power-grid technologies. Officials say this could pave the way for more resilient, affordable, and domestically sourced energy solutions.
Second, the mission is designed to advance fundamental scientific discovery. Through major investments in quantum research and closer collaboration with private industry, the United States hopes to build a robust ecosystem capable of generating transformative breakthroughs across physics, materials science, and biotechnology.
Finally, national security stands as a central pillar. The DOE will expand its use of AI computing to ensure the safety and reliability of the US nuclear stockpile, develop advanced materials for defence applications, and create new AI-driven tools to strengthen homeland security.
With the Genesis Mission now underway, the administration is positioning AI computing as the engine driving America’s next era of scientific and strategic leadership.
